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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6280a3ee2d86fa6d5adb4063e573cf3c49d73cd07857c3fa99c11fe9f913846a' 
  AND token = 'OTy2V+/4lj/GDeuKHQEgO2Suo6nkMfhLl79BBt5baFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}