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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7d3cad085ec0847287b7dac370aa25f008c641cd7dec35bf1e090ffaf4c67e0' 
  AND token = 'RPyUbDvgVAI3KH7aN3WpUIQGFapPa/35VGHVtRl7Y9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}