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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65890e86e602d5f48d5d42c3d8aa9a705b832df0f43ae7f70154e0509050121e' 
  AND token = 'ZFnzP+m/Yc3S2fdwtbr2faAMZt/vhj6Y++Otyjdn+EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}