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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '052cf981c2cfe3c6986e08db08a8aaaccd079e1ae3ec2e268dd3db19d91c6000' 
  AND token = 'wpOoO1bAwcHNhcSKs5sV5j5/8J3bI3GFS0OU2p5yUTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}