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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '042dae0a1798ca41ce5b0bee4c71381b0b22c9faeb2cf0f211682ea4431daf38' 
  AND token = 'KV51yAjPxQRvaHO8N+NyppAgVHvi8op6bZFTsWjexcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}