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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e2103d8857cb4d6b55edf730199a69bce6708ac9bfee662a0a60bd57ef1a1a6' 
  AND token = 'yPD08LIcjpdW3b/y3c/0TSdo4Z6NW6zdOGFTa1yNnGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}