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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15b155c75e8cb8ea5b1f5ec1d6ad1bedc484f5479ad3889a9da4911e69e86701' 
  AND token = '02LBtDuYSo4vfYTdCLyjzbOefb2Ek0gyxtSJE+4ImhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}