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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb27f3fb9577c9c5ee7582e6f56b48c7617d8cc64a3d856d325568db58f78dc' 
  AND token = '7D+dvw8Hp+XTdOEnCFlIo7Bm+rjU07ZpkTLSJxMDE5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}