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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8775a7b18c973124059f8b1813ca407f9d7a752323d013d8c1e2d11382b2970a' 
  AND token = 'PxU5CpQqd1AAHvP0np2GCxsw/wxUWOxn1y4j6hJ3Kp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}