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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9db27aa87dcf9d358b8392968f32e20b69355ee5f9c0ad5b8d7527e7c5157b22' 
  AND token = 'JQG+6W2Dm4nf/ooD20LJTTWwuLAb0WIjUPLosBCDNXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}