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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849fbfe976888b190ddcd2d4fe034f2f300f9e3e031808ad9dd550b4ac624a62' 
  AND token = 'eU8Hgk2UxOIbZsi0A+8YTNax9HIovYR87wQhj2XOcqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}