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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67396a2a1641161232bdd929bb13dde050f41809d5036a2dde03cf0668ce165f' 
  AND token = 'FdirtETcIenTNBx4l44lh4t8FBCtq2EXyFov0Cq/PD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}