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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf206b335bce9d580fd0cced0229ef55c775cfca56326abbe5071332c88ef7c4' 
  AND token = 'DGpoAJbe0NcyfDXV6rT3YgxY3whpa1WlBPRfg8mTF0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}