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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e530e21e090b4056e6ac423fbeb64192b82c23fea7397fd05d64dda6fbc9a69' 
  AND token = 'Ge8g4XlnC95crTlmRvOqK5n7Macf7rlS0KJozhtcFsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}