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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcb5b6a2e72214437f2089ad6a3c0290c8f438f80d741f1ecf0c2f4329b78663' 
  AND token = 'XOW8fvxl3hmNuCin6zLyYzEn2ojynV23WeqkkFMPLYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}