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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '050be2442823be09b788766c197fc7fa5d6ef0c714b3213f82bc7a1522302836' 
  AND token = 'mqeFULGt1hSoZJsi/5R93Yn5MKpl9d7VoTTcTEEjeGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}