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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '921f6ce09b196a3958c78a3092874834c1164e132b4a25432d77eae4a3297d82' 
  AND token = 'kPAVXm7ikA5ALFhGyqFMxqhU5qybFu0Xd5e1SOSq2fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}