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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fab3c5b1e3899440a1e88941d619b4b4a2d37c9ffa9e305447da596cdba32a8c' 
  AND token = 'r2kdhjXfeAXe4VmIVgy6vvDAzslLkEwCoJy5O8zpV2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}