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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70d51dc32ae3e9cc671f84d2bfc8675b2bb2c9b6ff356f39a1889e2fa728247e' 
  AND token = '+I1MEA9AlrIxdH1ADi8T12p0qrENqHBErc3qZMCCFIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}