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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4200da03c7e237d854126d9107439ed0ad21942f30f4425ab4c9fd1bb5c8aa28' 
  AND token = 'uHzCJKW1iBAZR5d/t9PdHiEqEn7ekYPl20BrkxeNt6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}