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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a89eda8323b0eaa217f4a43d35e28af9abd55c1154b4d116e7eeaf21848487f' 
  AND token = '0NQ9nbLC3n7gaaF+u/LfTV0vu3sK+fC/PU58seiKdUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}