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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37952320014353bb227d6523a88bcf0de6a010204e82b759dc81419cc2dd91f4' 
  AND token = 'rFKslr90BNKzdzj5SaHKJg8FQYBpmVxE3sCz6Ck8gkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}