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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8af7b2438407b2604157166944613b42c45496ba98debd1c6fd04b602a52e44b' 
  AND token = 'AyQwWshdTwp6JwnvEg3kwNjWcPqNi2f1Wcp/Np4fPZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}