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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40380428dff9b420e0fd4d69c45ea8112ea3557b70642722a9f0d32de3047f7f' 
  AND token = 'tDFqYEmEnq0C0ntERJ4LbsH06et5+IaqywE0bkXua4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}