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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d581d5efb0e3371e37d35fd89b39d8aaeeaadd2bb28c4f1a99a86b5a43660fc' 
  AND token = '57UxcgBYKvXpkARFTAfygCDtrZt1mSkZUvin945wiAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}