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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb50b909dbd4bcc68c533d34313e53355f2e204c2d6747b2979effabf71cbcfe' 
  AND token = '88q7VSyZc2VV/ZTWOX9Cuoz1O/ZFLY2b1cRpXnAfW9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}