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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17b907e6c5e0c235faeb8ef21b5c316faa77ebc72d02e3f1a9dd3e5779dbec64' 
  AND token = 'jly3P1Ef7CEdWEKfu97+9xUOojaZcZCf9vP23wS1gFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}