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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a5f9d40b9cfb1a27391234165818094a24f66db5d6a117573e480dfad65ecaa' 
  AND token = 'QLCJyIAYG2fFm86RLY1cUhc17WOY5rRHOl+2PR3Q3MY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}