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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0f2ebfb2616a5573eacea7a67016f05b9104ecb09f4f9c56d4ae48b8843f7ec' 
  AND token = 'Gc79/HJ4d848wLGGxdhwscRGRfCtzrdVbIpoxHFVE/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}