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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ded3cca6d8934cec2472bc78588f4c6b8378287078c4062e8569474dd4e4f383' 
  AND token = 'slt397UsgZ3yIHYkiL9P5IGysgAFMymGNq0HPlhllcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}