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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10114085b5d8ef4bf820f7049596cb9617fea8e64a0c89d5404d0391488e2f5e' 
  AND token = 'XlaP0m0V3Ll5jfvzHCF0XUvtRRt3419YvS1Nng11wZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}