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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '189ab8bff59120c3f73110a00a83fd81e587d6eb0b9265d5f9b717ff1bf2ee42' 
  AND token = 'NNL3+fTKL49SVKcF4QKJH36N+tA9rtwb4c+uZ9fk2YM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}