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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43425827ccdec8d4ad503ea87a79872cb9b995008710aa1a5abad4f9ab7e80b' 
  AND token = 'vWPS78cmLVVccmD6OJmNeWXzzE+9CY6m6xITZCMqCSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}