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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b10812c9290d8106a1fe8a872a07bf7dbefc93c1d3a44b98209acee2288cfc3' 
  AND token = 'VpT6/PQyRK+HB03CvHOpzjnQmaooaLyoZroEf0CXJ4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}