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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3859e9786853134041868a0fa03c587a94ce0756b3a27973a094d1bfa5a0bb48' 
  AND token = '9W0NIHSgBItuXKNohOF+lAGb4WtQZqBOVn9F9ElMF9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}