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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c82766be03e79809b2d389b3f18f9e98d62aa2b020da506526202d14f2afc14' 
  AND token = 'fGDHoxLuN/b6iA+f/5LtyVTDApqSe/JvJOqs8+5i3XY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}