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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ef759030831ab8fc1220d01622dea3f52111b27d0062321b632f15ff2258f0f' 
  AND token = 'XF1TnQGqGg9gHmOysRHB4bT9ik9fydSQKW5yrIhFZzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}