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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c49dfc7acd198593fd3ae36d99cd38e7fec35a1b289839af5b3c133b2f763929' 
  AND token = 'rmNvk6PWhHRKVr/BLM257b4EN+WcxgibscDTR6kSaL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}