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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a85bb2ba05573b1f9a68c29f36048e0d2462092ac82439de665e9e0a187e4ce' 
  AND token = 'xeIqB3EH56NlRqpl3xupCHxcEr5dvBuX1NKyxN8mHJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}