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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c78dc258d552e8f3350f154c2012225b372b628ddc693b4671a21b661394648' 
  AND token = 'Ezus7+l/E4+agOQpTOxcECmz7Cn4c67okRa9mmKg9jA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}