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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c54d2dfde2f4a0fe861c5deb1392000cd4997730d19d6b511aefe1e520a17da2' 
  AND token = 'OUM3Ud8E4uWsvxVlikVOb4j8pehtMBn/1rx7MYVNt3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}