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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a8590ffe27051f5afaf73c0c863f444bfc220390ba1642099524116102bdfb6' 
  AND token = 'X1kD5NNlsmmoOzbgc8KoPlEU+LPpgdVDcUYMSze9qzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}