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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1b5071e37301f2afa61dc8ea77b9d868656860facc31046b231249c8edde51' 
  AND token = 'Ve9RPp12qRUejjiN5CLp0ojFrv2k2bVWPizOHPwMTic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}