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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12d3901e0b1cbab619337c37be8c5ed3303e4a3d6aaeea4fb780cb8289b44955' 
  AND token = 'jee9DP6G+y7bimiQmRWhgsaYUeAb6aq/H2QWinI/am8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}