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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ffd677cb39ea11eaddd44e696a22080bb766384eb4c2fcddd4b4c75a2ad46f' 
  AND token = 'vNll7LyPFBdJZRfmX5RUX3FFnDn4yxXG7/zrx/qt+qE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}