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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6d3f89e0af8927bf045e76b96b333fd5eb90466a353e02591b7b73d6517901d' 
  AND token = 'OtIJt84hLPhLyzSuxId0M1aIIl7plu0fjEQW93QngQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}