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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d0722ac421face7beaf811b7722ce7bdb5f4a8f9113aa533f54671e260ae345' 
  AND token = 'xkcJRb1WDEMA4f0f78RlncSgKXYmgDrpq8LbPKE8Rxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}