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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb82df791ab82e514db2b481a11ab97bb2fc63da50e106a0bcb6c16efec861b' 
  AND token = 'p7raQmtFFnEkc1uGmbF33KpIOiGPqkcVx2dU441eBQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}