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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cc86a0647bd0a817a480248a25b0432a59fde3e79145e2c6c752756b7db1f54' 
  AND token = 'yFghWftxYRu/r2cxLmJ4OWmsbpzHVYlffYh0olF3F+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}