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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d3d989bcb873c08f15af08c40e9742480b74953f5a7ecf8deb2176a3b543fb' 
  AND token = 'DDteoHFGr0uu1bqAFMu+sBWgBlfQl833pKhfQioyKFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}